产品货号：
Z16043
中文名称：
EIF4B抗体
英文名称：
Anti-EIF4B Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-EIF4B Antibody |
| 指标别名 | EIF 4B;EIF4B;PRO1843 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,FCM,ELISA |
| 基因名称 | EIF4B |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human EIF4B recombinant protein (Position:M1-E611). |
| 实际分子量 | 80KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Eukaryotic translation initiation factor 4B is a protein that in humans is encoded by the EIF4B gene.Eukaryotic initiation factor 4B (eIF4B) is thought to assist the eIF4F complex in translation initiation.In plants,eIF4B is known to interact with the poly-(A) binding protein,increasing its poly-(A) binding activity.Heat shock and serum starvation cause dephosphorylation of eIF4B at multiple sites with kinetics similar to those of the corresponding inhibition of translation,while phosphorylation of eIF4B following insulin treatment correlates well with an observed increase in translation.Multiple kinases,including p70 S6 kinase,can phosphorylate eIF4B in vitro,and at least one serum-inducible eIF4B phosphorylation site is sensitive to rapamycin and LY294002.Recently,Ser406 was identified as a novel phosphorylation site regulated by mitogens,and the phosphorylation of this site is dependent on MEK and mTOR activity.This phosphorylation is shown to be essential for the translational activity of eIF4B. |
| Uniprot ID | P23588 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot. |
| 基因名全称 | eukaryotic translation initiation factor 4B |
| 蛋白名全称 | Eukaryotic translation initiation factor 4B |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells ELISA 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
相关搜索：EIF4B抗体，EIF4B多抗，Anti-EIF4B Antibody